Yes this is possible. You can override the whole Wwise streaming manager by reimplementing the AK::IAkStreamMgr interface, but the easiest is of course to implement the Low-Level I/O, which is a set of interfaces defined in the SDK header AkStreamMgrModule.h. You can start with the implementation provided in the SDK's samples, then replace the platform API calls with calls to open/read/close() of your own file I/O module.