The CAkDefaultIOHookDeferred low-level I/O hook sample (located in WWISESDK/samples/SoundEngine/Windows/) opens files with FILE_FLAG_NO_BUFFERING and FILE_FLAG_OVERLAPPED flags. These flags, combined with correctly aligned memory, give optimal unbuffered I/O performance according to the Windows' documentation (refer to ::CreateFile()'s documentation for more details, where FILE_FLAG_NO_BUFFERING is described).
In order to ensure that I/O buffers that are passed to the low-level I/O hook's Read() function are always correctly aligned, you need to
1) Allocate a streaming I/O pool that is aligned to the disk's sector. By default, the streaming I/O pool creation will end up calling the AK::VirtualAllocHook memory hook. See this article for more details.
2) Declare a block size that is a multiple of the disk's sector size. This is done by returning the proper value in your implementation of AK::StreamMgr::GetBlockSize() (see CAkDefaultIOHookDeferred::GetBlockSize()).