Audiokinetic's default stream manager creates a memory pool to perform I/O for each device (created using AK::CreateDevice()). These pools appear in the Wwise profiler under the name "Stream I/O". Their size is specified with AkDeviceSettings::uIOMemorySize. These pools are split up and managed in buffers of size AkDeviceSettings::uGranularity. Therefore, all buffers granted to clients of the AK::IAkStreamMgr interface, as well as I/O requests to the Low-Level I/O, have this same size.
Do not confuse the Stream I/O pools with the one and only Stream Manager pool. The latter is used for the Stream Manager's small objects that need to be allocated at run-time: device objects, stream objects, I/O request structures. It is typically very small. You should make sure that it is just large enough so that I/O does not fail because it is full: Stream I/O memory should be the bottleneck, not Stream Manager memory.